Radioembolisation for hepatocellular carcinoma].

J-L Raoul, J Edeline, M Pracht, E Boucher, Y Rolland, E Garin

Département d'oncologie médicale, centre Eugène-Marquis, rue de la bataille Flandres-Dunkerque, Rennes cedex, France. raoul@rennes.fnclcc.fr

Cancer radiothérapie : journal de la Société française de radiothérapie oncologique 2011 Feb

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Hepatocellular carcinoma is now a major public health concern. In intermediate stages (one third of hepatocellular carcinoma patients), chemoembolization is the standard of care despite a poor tolerance and a moderate efficacy. Moreover, despite recent improvements, this technique seems in a dead end. Radioembolization could be an excellent tool for such patients. Currently (131)I-Lipiodol, (188)Re-Lipiodol, (90)Y-glass or resin microspheres are available. More recent and promising data come from microspheres, but phase II and III studies are needed before drawing any conclusion. In the future, the combination of radioembolization with systemic chemotherapy or targeted agents (particularly antiangiogenic drugs) seems very promising. Copyright © 2010 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

Citation

J-L Raoul, J Edeline, M Pracht, E Boucher, Y Rolland, E Garin. Radioembolisation for hepatocellular carcinoma]. Cancer radiothérapie : journal de la Société française de radiothérapie oncologique. 2011 Feb;15(1):64-8