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Protein scaffolds coordinate the assembly of many multicomponent signaling complexes. Bodemann et al. (2011) now show that the exocyst, a protein complex involved in tethering transport vesicles to the plasma membrane, provides an assembly and activation platform for components of the autophagy machinery via a process requiring the GTPase RalB. Copyright © 2011 Elsevier Inc. All rights reserved.

Citation

Jean-Claude Farré, Suresh Subramani. Rallying the exocyst as an autophagy scaffold. Cell. 2011 Jan 21;144(2):172-4


PMID: 21241888

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