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PCNA (proliferating-cell nuclear antigen) is a ring-shaped protein that encircles duplex DNA and plays an essential role in many DNA metabolic processes. The PCNA protein interacts with a large number of cellular factors and modulates their enzymatic activities. In the present paper, we summarize the structures, functions and interactions of the archaeal PCNA proteins.

Citation

Miao Pan, Lori M Kelman, Zvi Kelman. The archaeal PCNA proteins. Biochemical Society transactions. 2011 Jan;39(1):20-4

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PMID: 21265741

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