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As nano-sizing is becoming a more common approach for pharmaceutical product development, researchers are taking advantage of the unique inherent properties of nanoparticles for a wide variety of applications. This article reviews the physical and chemical stability of drug nanoparticles, including their mechanisms and corresponding characterization techniques. A few common strategies to overcome stability issues are also discussed. Published by Elsevier B.V.


Libo Wu, Jian Zhang, Wiwik Watanabe. Physical and chemical stability of drug nanoparticles. Advanced drug delivery reviews. 2011 May 30;63(6):456-69

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PMID: 21315781

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