Green synthesis and stabilization of gold nanoparticles in chemically modified chitosan matrices.

Anand D Tiwari, Ajay K Mishra, Shivani B Mishra, Omotayo A Arotiba, Bhekie B Mamba

Department of Chemical Technology, University of Johannesburg, PO Box 17011, Doornfontein 2028, South Africa.

International journal of biological macromolecules 2011 May 1

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Chitosan-N-2-methylhydroxypyridine-6-methylcorboxylate (Ch-PDC) and chitosan-N-2-methylhydroxypyridine-6-methylhydroxy thiocarbohydrazide (Ch-PDC-Th) were synthesized for the first time using chitosan as precursor. Chitosan, Ch-PDC, Ch-PDC-Th were used in the synthesis of gold nanoparticles (AuNP) in aqueous medium. Chitosan and Ch-PDC-Th possess reducing properties which enabled the 'green' synthesis of AuNPs. The stabilization of the AuNPs was as a result of the thiocarbide (SC) and amine (NH(2)) groups in the chitosan matrix. The modified chitosan, its derivatives and the resulting AuNPs were characterized by Fourier transform infrared (FTIR) spectroscopy, Ultraviolet-visible (UV-vis) spectroscopy, Raman scattering measurements, powder X-ray diffraction (PXRD) and thermo gravimetric analysis (TGA). Particle size, morphology, segregation and individuality of the AuNPs were examined by transmission electron microscope (TEM) and energy dispersion spectroscopy (EDS). An average AuNPs size of 20 nm was observed for chitosan and Ch-PDC-Th while Ch-PDC was 50 nm. In comparison, AuNPs resulting from Ch-PDC-Th precursor has the most enhanced Raman and fluorescent intensities and was stable for over 2 months. Copyright © 2011 Elsevier B.V. All rights reserved.

Citation

Anand D Tiwari, Ajay K Mishra, Shivani B Mishra, Omotayo A Arotiba, Bhekie B Mamba. Green synthesis and stabilization of gold nanoparticles in chemically modified chitosan matrices. International journal of biological macromolecules. 2011 May 1;48(4):682-7