In response to major cellular insults, a massive increase in lysosomal membrane permeability (LMP) leads to necrosis. Data now reveal that this potent lysosomal-mediated necrotic cell-death machinery can also be harnessed for complex physiological processes, such as post-lactation mammary gland involution. © 2011 Macmillan Publishers Limited. All rights reserved
Cliff J Luke, Gary A Silverman. Necrotic cell death: harnessing the Dark side of the Force in mammary gland involution. Nature cell biology. 2011 Mar;13(3):197-9
PMID: 21364568
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