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We present a child with myoclonic seizures, epileptic spasms and generalized epileptiform discharges on scalp EEG. Magnetoencephalography and coherence-phase analysis for scalp EEG suggested focal onset in the left hemisphere. Intracranial video EEG confirmed seizure onset in the left frontal lobe with ictal high-frequency oscillations. Left frontal lobectomy suppressed his seizures. Subsets of myoclonic seizures can be focal in origin despite bilaterally synchronized epileptiform discharges on scalp EEG. Copyright © 2011 Elsevier B.V. All rights reserved.

Citation

Tomoyuki Akiyama, Elizabeth J Donner, Cristina Y Go, Ayako Ochi, O Carter Snead, James T Rutka, Hiroshi Otsubo. Focal-onset myoclonic seizures and secondary bilateral synchrony. Epilepsy research. 2011 Jun;95(1-2):168-72

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PMID: 21377332

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