Department of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South Korea. himun68@dau.ac.kr
Journal of enzyme inhibition and medicinal chemistry 2011 DecThe stems of Allium monanthum were extracted, and the major essential oil composition and larvicidal effects were studied. The analyses were conducted by gas chromatography and mass spectroscopy revealed that the essential oils of A. monanthum stems. The A. monanthum essential oil yield was 4.25%, and gas chromatography and mass spectroscopy analysis revealed that its major constituents were dimethyl trisulfide (23.21%), dimethyl tetrasulfide (11.24%) and methlyl propyl trisulfide (8.21%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC(50) value of 23.14 ppm and an LC(90) value of 36.31 ppm. Also, dimethyl trisulfide (≥95.0%), dimethyl tetrasulfide (≥95.0%) and methlyl propyl trisulfide (≥95.0%) were tested against the F(21) laboratory strain of A. aegypti. Methlyl propyl trisulfide (≥95.0%) has good activity with an LC(50) value of 19.38 ppm. Also, the above indicates that other major compounds may play a more important role in the toxicity of essential oil.
Hyung-In Moon. Larvicidal activity of major essential oils from stems of Allium monanthum Maxim. against Aedes aegypti L. Journal of enzyme inhibition and medicinal chemistry. 2011 Dec;26(6):827-30
PMID: 21417962
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