The epigenetics of Alzheimer's disease--additional considerations.

Joseph Rogers, Diego Mastroeni, Andrew Grover, Elaine Delvaux, Charisse Whiteside, Paul D Coleman

Banner Sun Health Research Institute, Sun City, AZ, USA. joseph.rogers@bannerhealth.com

Neurobiology of aging 2011 Jul

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The critical commentaries following our review of the epigenetics of Alzheimer's disease (AD) amplify a number of key points with respect to the role of 1-carbon metabolism, the phenomenon of allele-specific methylation, the potentially critical explanatory link provided by epigenetic mechanisms for genome-wide association and large-scale gene expression array studies, and new therapeutic approaches afforded by epigenetic manipulation in Alzheimer's disease. Copyright © 2011 Elsevier Inc. All rights reserved.

Citation

Joseph Rogers, Diego Mastroeni, Andrew Grover, Elaine Delvaux, Charisse Whiteside, Paul D Coleman. The epigenetics of Alzheimer's disease--additional considerations. Neurobiology of aging. 2011 Jul;32(7):1196-7