PtrA is a periplasmic protein involved in Cu tolerance in Pseudomonas aeruginosa.

Sylvie Elsen, Michel Ragno, Ina Attree

Bacterial Pathogenesis and Cellular Responses, iRTSV, CEA-Grenoble, Grenoble cedex 09, France. sylvie.elsen@cea.fr

Journal of bacteriology 2011 Jul

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In this work, we demonstrate that PtrA (U. H. Ha et al., Mol. Microbiol. 54:307-320, 2004) is a periplasmic protein, specifically synthesized in the presence of copper, that is involved in the tolerance of Pseudomonas aeruginosa to copper. Our biochemical and genetic analyses challenge its role in transcriptional inhibition of the type III secretion system.

Citation

Sylvie Elsen, Michel Ragno, Ina Attree. PtrA is a periplasmic protein involved in Cu tolerance in Pseudomonas aeruginosa. Journal of bacteriology. 2011 Jul;193(13):3376-8