Siliconorganic reversible inhibitors of cholinesterases of various animals].

E V Rozengart, N E Basova

Zhurnal evoliutsionnoĭ biokhimii i fiziologii 2011 Mar-Apr

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The review present data on cholinesterase effects of 28 specially synthesized siliconorganic compounds (monoonium, clementorganic, and bisonium derivatives) studied as reversible inhibitors of acetylcholinesterase (acetyl-ChE) of human erythrocytes, butyryl-ChE of horse blood serum, ChE of brain of common frog Rana temporaria, ChE of the optical ganglia tissue of Pacific squid Todarodes pacificus and of individuals of Commandor squid Berryteuthis magister from various habitats in the Northwestern aquatoria of the Pacific ocean. Among the tested compounds, there are revealed highly specific inhibitors of mammalian ChE as well as of ChE of the B. magister individuals from various habitats.

Citation

E V Rozengart, N E Basova. Siliconorganic reversible inhibitors of cholinesterases of various animals]. Zhurnal evoliutsionnoĭ biokhimii i fiziologii. 2011 Mar-Apr;47(2):113-9