X-ray crystallography and the elucidation of the structure of DNA.

Department of Radiology, Indiana University School of Medicine, 702 Barnhill Dr, Rm 1053, Indianapolis, IN 46202-5200, USA.

AJR. American journal of roentgenology 2011 Jun

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Since their discovery by Roentgen in 1895, x-rays have contributed to some of the most important advances in science. X-ray crystallography is an imaging technique that uses x-ray diffraction to evaluate the molecular structure of a crystalline solid. This article discusses the critical role played by x-ray crystallography in the elucidation of the structure of DNA. The story of DNA includes insights on molecular structure provided by x-rays and also lessons on scientific collaboration and innovation that can be applied to radiology today.

Citation

Hugh C J McGregor, Richard B Gunderman. X-ray crystallography and the elucidation of the structure of DNA. AJR. American journal of roentgenology. 2011 Jun;196(6):W689-92