Recent advance in the genomic study for osteoarthritis].

Laboratory for Bone and Joint Diseases, Center for Genomic Medicine, RIKEN, Japan.

Clinical calcium 2011 Jun

Osteoarthritis (OA) is a polygenic disease. Genetic factors are involved in its onset and progression. Identification of its genetic factor, i.e., the susceptibility genes for OA is rapidly in progress by using genomic approaches including genome-wide association study. Recent advance in the study of OA susceptibility genes is reviewed.