Drimane sesquiterpenoids from the mangrove-derived fungus Aspergillus ustus.

Huinan Zhou, Tianjiao Zhu, Shengxin Cai, Qianqun Gu, Dehai Li

Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, P.R. China.

Chemical & pharmaceutical bulletin 2011

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Five new drimane sesquiterpenes (1-5) together with 14 known analogues (6-19) were isolated from laboratory cultures of a mangrove-derived fungus Aspergillus ustus. Their structures were established by spectroscopic methods and antitumor activities were evaluated by sulforhodamine B (SRB) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods.

Citation

Huinan Zhou, Tianjiao Zhu, Shengxin Cai, Qianqun Gu, Dehai Li. Drimane sesquiterpenoids from the mangrove-derived fungus Aspergillus ustus. Chemical & pharmaceutical bulletin. 2011;59(6):762-6