Resolution of galactomannan antigenemia in a patient receiving oral voriconazole for chronic necrotizing pulmonary aspergillosis.

Chi-Jung Wu, Hsin-Chun Lee, Hsiu-Jung Lo, Wen-Chien Ko

Division of Clinical Research/Infectious Diseases, National Health Research Institutes, Zhunan, Miaoli County 350, Taiwan.

Diagnostic microbiology and infectious disease 2011 Aug

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The serologic markers of the therapeutic response of chronic necrotizing pulmonary aspergillosis (CNPA) are rarely reported. Here, we describe the changes in galactomannan (GM) antigenemia in a patient receiving oral voriconazole for CNPA, in whom a resolution of GM antigenemia to a normal level was associated with clinical improvements. The serum GM index can be an adjunctive tool for the diagnosis and monitoring of the therapeutic response of CNPA. Copyright © 2011 Elsevier Inc. All rights reserved.

Citation

Chi-Jung Wu, Hsin-Chun Lee, Hsiu-Jung Lo, Wen-Chien Ko. Resolution of galactomannan antigenemia in a patient receiving oral voriconazole for chronic necrotizing pulmonary aspergillosis. Diagnostic microbiology and infectious disease. 2011 Aug;70(4):528-30