Anti-resorptive activity and pharmacokinetic study of N(1),N(1)-diisopropyl-N(2)-(diphenylphosphoryl)-2-(4-nitrophenyl)acetamidine.

Myung Hee Kim, Mikyung Park, Jin Sook Song, Sang-Joon Park, Seong Hwan Kim

Laboratory of Chemical Genomics, Bio-Organic Science Division, Korea Research Institute of Chemical Technology, Sinseongno 19, Yuseong-gu, Daejeon 305-600, Republic of Korea.

Bioorganic & medicinal chemistry letters 2011 Jul 15

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In vitro anti-resorptive activity, mechanism of action, pharmacokinetic profile and in vivo anti-resorptive activity of N(1),N(1)-diisopropyl-N(2)-(diphenylphosphoryl)-2-(4-nitrophenyl)acetamidine (1) were evaluated. Copyright © 2011 Elsevier Ltd. All rights reserved.

Citation

Myung Hee Kim, Mikyung Park, Jin Sook Song, Sang-Joon Park, Seong Hwan Kim. Anti-resorptive activity and pharmacokinetic study of N(1),N(1)-diisopropyl-N(2)-(diphenylphosphoryl)-2-(4-nitrophenyl)acetamidine. Bioorganic & medicinal chemistry letters. 2011 Jul 15;21(14):4263-6