Correlation of band 3 protein in erythrocytes with physiological status of middle-aged and elderly people].

To analyze the correlation of band 3 protein of erythrocytes with physiological conditions of middle-aged and elderly people, and to investigate the expression of band 3 protein under different physiological status. Cluster randomized sampling method for selecting subjects . Physical examination data and blood samples of 218 middle-aged and elderly people (80 males and 138 females) were collected. SDS-polyacrylamide gel electrophoresis was used to analyze band 3 protein in erythrocyte membrane. The difference of band 3 protein in different groups was analyzed by T Test and One-Way ANOVA. Correlation and regression of band 3 protein with physiological status was analyzed by Pearson correlation and linear regression. There was a significantly positive correlation (r =0.149) between the level of band 3 protein and physical activity (P <0.05), and a negative correlation (r = -0.156) between the level of band 3 protein and systolic blood pressure (P <0.05). The correlation of band 3 protein with gender, age, BMI and diastolic blood pressure (P >0.05) is not significant. The band 3 protein level of workers with medium activity was 24. 09% , which was significantly higher than that of light activity workers (23.42%) (P <0.05). The subjects with hypertension were proved to have a significantly lower level of band 3 protein (23.33%) than normal individuals (24.20%) (P < 0.05). The level of band 3 protein was positively correlated with physical activity and negatively correlated with systolic blood pressure.

Citation

Wenlu Chang, Yongye Sun, Qiuzhen Wang, Wei Du, Xueqian Wu, Aigou Ma. Correlation of band 3 protein in erythrocytes with physiological status of middle-aged and elderly people]. Wei sheng yan jiu = Journal of hygiene research. 2011 May;40(3):323-6

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PMID: 21695904

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