In vivo evidence that retinal bipolar cells generate spikes modulated by light.

Elena Dreosti, Federico Esposti, Tom Baden, Leon Lagnado

Nature neuroscience 2011 Jun 26

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Retinal bipolar cells have been assumed to generate purely graded responses to light. To test this idea we imaged the presynaptic calcium transient in live zebrafish. We found that ON, OFF, transient and sustained bipolar cells are all capable of generating fast 'all-or-none' calcium transients modulated by visual stimulation.

Citation

Elena Dreosti, Federico Esposti, Tom Baden, Leon Lagnado. In vivo evidence that retinal bipolar cells generate spikes modulated by light. Nature neuroscience. 2011 Jun 26;14(8):951-2