Rapid urinary output normalization method using specific gravity.

Spot urine samples are often taken for emergency radiobioassay to provide a quick dose assessment for contaminated individuals. The subsequent dosimetric analysis requires a urinary output normalization method to adjust spot sampling to daily urine excretion. A rapid specific gravity method that was developed for 24-h urinary output correction is described. Spot urine samples were collected from volunteers of different race, gender, and age to validate the normalization method. Results show that a specific gravity test is a fast, easy and robust method to correct the urine excretion in the event of a radiation emergency.

Citation

Xiongxin Dai, Kaitlyn Kutschke, Nicholas Priest. Rapid urinary output normalization method using specific gravity. Health physics. 2011 Aug;101(2):140-3

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PMID: 21709500

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