Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate.

Nobuki Okubo, Takahisa Fujita, Yoshihito Ishii, Mikio Ota, Yoshihiro Shibukawa, Satoru Yamada

Department of Periodontology, Tokyo Dental College, 1-2-2, Masago Mihama-ku, Chiba, 261-8502, Japan. ookubonobuki@tdc.ac.jp

Journal of biomaterials applications 2013 Jan

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The aim of this study was to investigate the effect of beta-tricalcium phosphate (β-TCP) particles in combination with acellular dermal matrix (ADM) allograft in gingival recession. Experimental gingival recession defects were created in beagle dogs and randomly assigned to one of the following groups: ADM, ADM + β-TCP, or coronally positioned flap (CPF; control). Tissues were histologically examined at 4, 8, or 16 weeks following treatment. A greater thickness of gingiva was observed at the sites treated in both the ADM + β-TCP and ADM groups than in the CPF group. The ADM + β-TCP group showed a statistically significant increase in both new bone and cementum formations compared to the ADM group. The results suggest that the combination of β-TCP and ADM is more effective in promoting new bone and cementum formations than ADM graft alone.

Citation

Nobuki Okubo, Takahisa Fujita, Yoshihito Ishii, Mikio Ota, Yoshihiro Shibukawa, Satoru Yamada. Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate. Journal of biomaterials applications. 2013 Jan;27(5):627-37