Fixation behavior in primary open angle glaucoma at early and moderate stage assessed by the MicroPerimeter MP-1.

Using MicroPerimetry MP-1 to assess the fixation behavior in early and moderate primary open angle glaucoma (POAG). Thirty-nine early and moderate POAG eyes and 22 normal eyes were enrolled prospectively. The stability and location of the fixation in each subject eye were recorded by the macula 10-degree program of the microperimeter (MP-1). Retinal sensitivity was examined using the G2 program phase 1 of an Octopus 101 perimeter and the macula 10-degree program of the MP-1. The fixation behavior and the retinal sensitivity were compared between POAG and control groups. The correlation between the fixation behavior and the retinal sensitivity was analyzed in POAG patients. : Fixation instability was detected in POAG (P=0.016). It correlated with the mean defect on Octopus perimeter and all the mean macular sensitivity parameters of MP-1, which includes the central 10 degrees (r=0.416, P=0.008), 6 degrees (r=0.401, P=0.011), 2 degrees (r=0.376, P=0.018), inferotemporal (r=0.399, P=0.012) and inferonasal (r=0.387, P=0.015) quadrants of the central 6 degrees. All the POAG patients had a predominantly central fixation. Fixation instability manifested in early and moderate POAG eyes, which may be an early sign of POAG.

Citation

Yan Shi, Mugen Liu, Xin Wang, Chun Zhang, Ping Huang. Fixation behavior in primary open angle glaucoma at early and moderate stage assessed by the MicroPerimeter MP-1. Journal of glaucoma. 2013 Feb;22(2):169-73

Mesh Tags

PMID: 21946547

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