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A 9-step synthetic route to the complex carbohydrate methyl α-trioxacarcinoside B from 2-acetylfuran is described. Anomerically activated forms, including 1-phenylthio, 1-O-(4'-pentenyl), 1-fluoro, and 1-O-acetyl derivatives are also prepared. © 2011 American Chemical Society

Citation

Thomas Magauer, Andrew G Myers. Short and efficient synthetic route to methyl α-trioxacarcinoside B and anomerically activated derivatives. Organic letters. 2011 Oct 21;13(20):5584-7

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PMID: 21958151

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