Two new abietane diterpenoids from the caulis and leaves of Callicarpa kochiana.

Chao-Zhan Lin, Chen-Chen Zhu, Zhong-Xiang Zhao, Xiao-Hui Li, Tian-Qin Xiong, Yu-Ying Xia, Yu Ning

School of Chinese Materia Medica, Guangzhou University of Chinese Medicine, Guangzhou, 510006, PR China.

Fitoterapia 2012 Jan

filter terms:

Previous studies revealed that diterpenoids from Callicarpa genus were mainly of clerodane-type and phyllocladane-type, and abietane-type diterpenoids were seldom reported. In this paper, we reported two new abietane diterpenoids, kochianic acid A (1) and kochianic acid B (2), together with two known abietane-type diterpenoids, pedunculatic acid B (3) and 7α, 15-dihydroxydehydroabietic acid (4), which were all isolated from Callicarpa kochiana. The structures of the new compounds 1 and 2 were elucidated on the basis of extensive spectroscopic analysis, including HSQC, HMBC, (1)H-(1)H COSY, ROESY and finally confirmed by single-crystal X-ray diffraction. Copyright © 2011 Elsevier B.V. All rights reserved.

Citation

Chao-Zhan Lin, Chen-Chen Zhu, Zhong-Xiang Zhao, Xiao-Hui Li, Tian-Qin Xiong, Yu-Ying Xia, Yu Ning. Two new abietane diterpenoids from the caulis and leaves of Callicarpa kochiana. Fitoterapia. 2012 Jan;83(1):1-5