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In addition to lupeol (1a), three long-chain alkanoic acid esters of lupeol, in which two were new, were isolated from the hexane and ethyl acetate twigs extract of Dorstenia harmsiana Engl. (Moraceae). The structures of the new compounds were elucidated on the basis of 1D and 2D NMR experiments. Some isolated compounds were evaluated for their antimicrobial activities. The lupeol and its three long-chain alkanoic acid esters showed antifungal and antibacterial activities.


Herve Martial P Poumale, Kenzo Patrice Awoussong, Rivoarison Randrianasolo, Christophe Colombe F Simo, Bonaventure Tchaleu Ngadjui, Yoshihito Shiono. Long-chain alkanoic acid esters of lupeol from Dorstenia harmsiana Engl. (Moraceae). Natural product research. 2012;26(8):749-55

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PMID: 21999356

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