Association between metabolic syndrome and parameters of 24-hour blood pressure ambulatory monitoring.

To investigate associations between metabolic syndrome (MS) and 24-hour blood pressure parameters as a measure of cardiovascular risk (CVR). 136 hypertensive subjects, of both sexes, aged between 29 and 83 years were studied. CVR was defined as having at least three of the following conditions: 1) systolic/diastolic blood pressure (BP) ≥ 140/90 mmHg, absence/attenuation of nighttime fall in BP during sleep, pulse pressure (PP) ≥ 53 mmHg; 2) 24-h PP > 53 mmHg, 3) nighttime PP > 53 mmHg, 4) daytime PP > 53 mmHg and 5) nighttime fall in BP during sleep. The 24-h PP, daytime PP and nighttime PP were elevated in 54% of the population. Hypertriglyceridemia (52%), low HDL (72.8%), abdominal obesity (60.3%), MS (58.1%), dyslipidemia (88.8%), overweight (74.3%) and obesity (33.8%) were also elevated. Age-adjusted MS was associated with higher CVR (OR = 4.5 and 3.6), 24-h PP (OR = 2.3 and 4.7), and daytime PP (OR = 2.2 and 4.6). MS was highly prevalent and correlated with altered 24-hour blood pressure parameters.

Citation

Mariana Santos Felisbino-Mendes, Tatiane Géa-Horta, Antônio Luiz Pinho Ribeiro, Gilberto Kac, Salete Maria de Fátima Silqueira, Gustavo Velásquez-Meléndez. Association between metabolic syndrome and parameters of 24-hour blood pressure ambulatory monitoring. Arquivos brasileiros de endocrinologia e metabologia. 2011 Aug;55(6):383-8

Mesh Tags

PMID: 22011854

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