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The sixth edition of the Conference on Recombinant Protein Production saw a return of physiology-based cell and process engineering. While the application of omics technologies to cell engineering has been constantly on the rise during the past decade, the concept of systems biotechnology is now also applied on bioprocesses bringing new insights into process design and production strategies. The conference brought an extensive comparative view on host cell physiology, covering all areas of bacterial, yeast, fungal, insect, plant and mammalian protein production hosts. Global (genome scale) cellular analysis led to local cell engineering strategies covering also interspecies host optimization strategies, and bringing energy requirements during recombinant protein production back into focus. Additionally, the development of novel secretion systems was presented, giving one example of how to combine industry's needs with highly ambitious fundamental research. Copyright © 2011. Published by Elsevier B.V. All rights reserved.


Brigitte Gasser, Diethard Mattanovich, Michael Sauer, Michael Maurer. Recombinant protein production 6 (Vienna, February 2011). New biotechnology. 2013 Jan 25;30(2):247-9

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PMID: 22032951

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