Ayako Osawa, Asami Kasahara, Shoko Mastuoka, Sören Gassel, Gerhard Sandmann, Kazutoshi Shindo
Department of Food and Nutrition, Japan Women's University, Tokyo, Japan.
Bioscience, biotechnology, and biochemistry 2011In the course of screening for antioxidative carotenoids from bacteria, we isolated and identified a novel carotenoid, OH-chlorobactene glucoside hexadecanoate (4), and rare carotenoids, OH-chlorobactene glucoside (1), OH-γ-carotene glucoside (2) and OH-4-keto-γ-carotene glucoside hexadecanoate (3) from Rhodococcus sp. CIP. The singlet oxygen ((1)O(2)) quenching model of these carotenoids showed potent antioxidative activities IC(50) 14.6 µM for OH-chlorobactene glucoside hexadecanoate (4), 6.5 µM for OH-chlorobactene glucoside (1), 9.9 µM for OH-γ-carotene glucoside (2) and 7.3 µM for OH-4-keto-γ-carotene glucoside hexadecanoate (3).
Ayako Osawa, Asami Kasahara, Shoko Mastuoka, Sören Gassel, Gerhard Sandmann, Kazutoshi Shindo. Isolation of a novel carotenoid, OH-chlorobactene glucoside hexadecanoate, and related rare carotenoids from Rhodococcus sp. CIP and their antioxidative activities. Bioscience, biotechnology, and biochemistry. 2011;75(11):2142-7
PMID: 22056433
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