Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus.
Johannes Schneider, Ana Yepes, Juan C Garcia-Betancur, Isa Westedt, Benjamin Mielich, Daniel López
Institute for Molecular Infection Biology IMIB, Centre for Molecular Research in Infectious Disease ZINF, University of Würzburg, Würzburg, Germany.
Applied and environmental microbiology 2012 JanBacillus subtilis induces expression of the gene ytnP in the presence of the antimicrobial streptomycin, produced by the Gram-positive bacterium Streptomyces griseus. ytnP encodes a lactonase-homologous protein that is able to inhibit the signaling pathway required for the streptomycin production and development of aerial mycelium in S. griseus.
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Johannes Schneider, Ana Yepes, Juan C Garcia-Betancur, Isa Westedt, Benjamin Mielich, Daniel López. Streptomycin-induced expression in Bacillus subtilis of YtnP, a lactonase-homologous protein that inhibits development and streptomycin production in Streptomyces griseus. Applied and environmental microbiology. 2012 Jan;78(2):599-603
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PMID: 22101040
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