Research advances of diterpene synthase].

Yun-fei He, Wei Gao, Ta-si Liu, Wen-yuan Li, Lu-qi Huang

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Yao xue xue bao = Acta pharmaceutica Sinica 2011 Sep

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Diterpenes, an important class of natural compounds, are widely distributed in nature. As the valuable diterpenoids continue to be found, diterpene synthase in the course of diterpene synthesis get as much attention as possible. The multiformity of end-product-diterpenoids were also due to the diversity of diterpene synthase. This paper focuses on the advances in recent biosynthesis pathway of diterpene and types, cloning, catalytic mechanism, synthetic biology application.

Citation

Yun-fei He, Wei Gao, Ta-si Liu, Wen-yuan Li, Lu-qi Huang. Research advances of diterpene synthase]. Yao xue xue bao = Acta pharmaceutica Sinica. 2011 Sep;46(9):1019-25