The suprachiasmatic nucleus is the primary circadian pacemaker in mammals. In turn, the suprachiasmatic nucleus influences circadian physiology, endocrinology and behavior via the synchronization of local oscillators that are operative in the cells of most organs and tissues. Thus circadian pacemaker may play an important role in psychiatric disorders and in psychotherapeutic drugs effect. In this review, we summarize data about the suprachiasmatic nuclei anatomy, physiology and pharmacological sensitivity.
É B Arushanian, A V Popov. Recent data about the role of hypothalamic suprachiasmatic nucleus in circadian organization of physiological functions]. Uspekhi fiziologicheskikh nauk. 2011 Oct-Dec;42(4):39-58
PMID: 22145310
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