Bing Han, Xiu-Long Yang, Chao Wang, Yong-Wei Bai, Tai-Chao Pan, Xin Chen, Wei Yu
State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, 222 Tianshui Street, Lanzhou 730000, P. R. China. hanb@lzu.edu.cn
The Journal of organic chemistry 2012 Jan 20The Cu/N-ligand/TEMPO catalytic system was first applied to the aerobic oxidative synthesis of heterocycles. As demonstrated, 2-substituted quinazolines and 4H-3,1-benzoxazines were synthesized efficiently from the one-pot reaction of aldehydes with 2-aminobenzylamines and 2-aminobenzyl alcohols, respectively, by employing CuCl/DABCO/4-HO-TEMPO as the catalysts and oxygen as the terminal oxidant.
Bing Han, Xiu-Long Yang, Chao Wang, Yong-Wei Bai, Tai-Chao Pan, Xin Chen, Wei Yu. CuCl/DABCO/4-HO-TEMPO-catalyzed aerobic oxidative synthesis of 2-substituted quinazolines and 4H-3,1-benzoxazines. The Journal of organic chemistry. 2012 Jan 20;77(2):1136-42
PMID: 22168403
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