Acid-base and electrolyte status during early induced pregnancy toxaemia in goats.

Félix H Díaz González, Fuensanta Hernández, Josefa Madrid, Silvia Martínez-Subiela, José Joaquín Cerón, Fernando Tecles

Veterinary School, Federal University of Rio Grande do Sul, Av. Bento Gonçalves 9090, Porto Alegre, Brazil.

Veterinary journal (London, England : 1997) 2012 Aug

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Eleven Murciano-Granadina goats in late pregnancy were separated into two groups (1) control (n=6) and (2) fasting for 72 h to induce pregnancy toxaemia (n=5). Venous blood was taken daily to determine acid-base and electrolyte parameters. Significant decreases in blood pH, bicarbonate concentration and base excess, and a significant increase in anion gap were observed after 24h of fasting. These changes were significantly correlated with non-esterified fatty acid concentration. No significant changes were observed in pCO(2), and electrolyte or lactate concentrations. Clinical signs of pregnancy toxaemia in fasted goats appeared by 72h post-fasting. These signs and the changes in acid-base balance disappeared once feed was reintroduced. Blood pH, bicarbonate concentration, base excess and anion gap could be indicators of early pregnancy toxaemia in goats. Copyright © 2011 Elsevier Ltd. All rights reserved.

Citation

Félix H Díaz González, Fuensanta Hernández, Josefa Madrid, Silvia Martínez-Subiela, José Joaquín Cerón, Fernando Tecles. Acid-base and electrolyte status during early induced pregnancy toxaemia in goats. Veterinary journal (London, England : 1997). 2012 Aug;193(2):598-9