Olanzapine-associated myoclonus.

Jennifer Block Rosen, Mark J Milstein, Sheryl R Haut

Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA.

Epilepsy research 2012 Feb

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Olanzapine is an atypical antipsychotic drug that infrequently has been reported to cause seizures and myoclonus despite a small proconvulsant risk. This is the first report of generalized myoclonus induced in a patient who had been maintained on low dose olanzapine for over seven years without any change in her dose. Olanzapine was discontinued, and the myoclonic jerks completely resolved within 48 h. Copyright © 2011. Published by Elsevier B.V.