Bacterial chromosome segregation.

Dividing cells have mechanisms to ensure that their genomes are faithfully segregated into daughter cells. In bacteria, the description of these mechanisms has been considerably improved in the recent years. This review focuses on the different aspects of bacterial chromosome segregation that can be understood thanks to the studies performed with model organisms: Escherichia coli, Bacillus subtilis, Caulobacter crescentus and Vibrio cholerae. We describe the global positionning of the nucleoid in the cell and the specific localization and dynamics of different chromosomal loci, kinetic and biophysic aspects of chromosome segregation are presented. Finally, a presentation of the key proteins involved in the chromosome segregation is made.

Citation

Christophe Possoz, Ivan Junier, Olivier Espeli. Bacterial chromosome segregation. Frontiers in bioscience (Landmark edition). 2012 Jan 01;17(3):1020-34

Mesh Tags

PMID: 22201788

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