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Kinetochore dynamics: how protein dynamics affect chromosome segregation.

Jonas F Dorn, Paul S Maddox

Institute for Research in Immunology and Cancer (IRIC), Department of Pathology and Cell Biology, Université de Montréal, P.O. Box 6128, Station Centre-Ville, Montréal, QC, H3C 3J7, Canada.

Current opinion in cell biology 2012 Feb


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  • animals (1)
  • cell cycle proteins (2)
  • chromosome segregation (3)
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  • kinetochore (4)
  • mitosis (3)
  • mitotic spindle apparatus (1)
  • motility (1)
  • nuclear proteins (2)
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    Protein dynamics generate adaptive cellular architecture. This concept is exemplified by kinetochores, organelles that orchestrate chromosome segregation during mitosis. In this review, we will focus on protein dynamics at kinetochores and discuss how these dynamics impact chromosome motility during mitosis. Copyright © 2012 Elsevier Ltd. All rights reserved.

    Citation

    Jonas F Dorn, Paul S Maddox. Kinetochore dynamics: how protein dynamics affect chromosome segregation. Current opinion in cell biology. 2012 Feb;24(1):57-63

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    PMID: 22209729

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