Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Metal ions stabilize quadruplex nucleic acids by coordinating the O6 guanine atoms from G-quartets. These quartets form the basic motif of quadruplex structures. This article systematically surveys the available crystallographic data on native quadruplexes, their ligand complexes and (in one instance) a protein complex. Three categories of quadruplex are examined, tetramolecular, bimolecular, and intramolecular: all are formed by telomeric nucleic acid sequences from human or ciliate organisms.


Nancy H Campbell, Stephen Neidle. G-quadruplexes and metal ions. Metal ions in life sciences. 2012;10:119-34

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 22210337

View Full Text