Actinobaculum schaalii, a cause of urinary tract infections in children?

To inform that Actinobaculum schaalii can colonize the urine and cause urinary tract infection in children. Urine samples were examined by wet smear microscopy, incubated in 5% CO(2) for 1-2 days, and species-specific real-time polymerase chain reaction (PCR) for A. schaalii was performed. In 5 of the 29 screened urines, A. schaalii was found only by real-time PCR in quantities equivalent to ≥ 10(4) -10(5) CFU/mL. In addition, A. schaalii was found in quantities equivalent to ≥ 10(6) CFU/mL by both culture and PCR in two children with a urinary tract infection and large numbers of leucocytes in the urine. Actinobaculum schaalii is CO(2)-dependent. Therefore, if there are clinical symptoms and/or a negative culture despite the presence of leucocytes in the urine, Gram staining and incubation in 5% CO(2) or species-specific real-time PCR should be performed to identify A. schaalii. © 2011 The Author(s)/Acta Paediatrica © 2011 Foundation Acta Paediatrica.

Citation

Lise Bols Andersen, Steffen Bank, Birgitte Hertz, Karen Marie Søby, Jørgen Prag. Actinobaculum schaalii, a cause of urinary tract infections in children? Acta paediatrica (Oslo, Norway : 1992). 2012 May;101(5):e232-4

Mesh Tags

PMID: 22211919

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