F-18 FDG and C-11 methionine PET/CT in intracranial dural metastases.

Maria Mathew D'Souza, Abhinav Jaimini, Madhavi Tripathi, Naresh Garg, Rajnish Sharma, Anupam Monndal, Rajendra P Tripathi

Division of PET Imaging, Molecular Imaging and Research Center, INMAS, Delhi, India. maria.md@rediffmail.com

Clinical nuclear medicine 2012 Feb

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A 58-year-old woman with breast carcinoma, after mastectomy, radiotherapy, and chemotherapy, underwent a whole-body F-18 FDG PET/CT for restaging, which revealed multiple skeletal metastasis. Hypometabolism was noted in the right frontal lobe. The patient subsequently underwent a C-11 methionine brain scan, which demonstrated multiple dural-based metastatic foci confirmed on contrast-enhanced MR. FDG PET has limitations in brain tumor detection. Amino acid tracers are particularly attractive for imaging of brain tumors because of relatively high tumor to brain activity ratios.

Citation

Maria Mathew D'Souza, Abhinav Jaimini, Madhavi Tripathi, Naresh Garg, Rajnish Sharma, Anupam Monndal, Rajendra P Tripathi. F-18 FDG and C-11 methionine PET/CT in intracranial dural metastases. Clinical nuclear medicine. 2012 Feb;37(2):206-9