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A FlAsH of potential: the specific binding of the biarsenical probe to the tetracysteine motif has matured as a tool for cell biology studies. Combining two such binders in one probe generates a useful reporter of protein dimerization events. The current state of art and the perspective for future developments are highlighted. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Thorsten Stafforst. A FlAsH reporter for protein-dimerization triggers. Chembiochem : a European journal of chemical biology. 2012 Mar 5;13(4):505-7

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PMID: 22278994

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