Study of pathogenesis of Anaprilin toxicological influence in analysis of central hemodynamic indices and myocardial contractility of isolated heart in experiment].

V T Dolgikh, B B Iatsiniuk, V G Sentsov, K M Brusin

Patologicheskaia fiziologiia i èksperimental'naia terapiia 2011 Jul-Sep

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Anaprilin under one-shot intraperitoneal introduction to dose 1 and 2 milligrams to 100 grams of animal's body weight causes depending on dose of the change system hemodynamic, myocardial contractility and biochemical factors shelters rats. Anaprilin under one-shot introduction to dose 2 miligrams to 100 grams of animal's body weight change myocardial contractility of isolated heart which were force evidented in the conditions of hypercalcium perfusion and reperfusion.

Citation

V T Dolgikh, B B Iatsiniuk, V G Sentsov, K M Brusin. Study of pathogenesis of Anaprilin toxicological influence in analysis of central hemodynamic indices and myocardial contractility of isolated heart in experiment]. Patologicheskaia fiziologiia i èksperimental'naia terapiia. 2011 Jul-Sep(3):29-34