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We present a colorimetric and ratiometric fluorescent probe Cy-N(3) that exhibits a selective response to H(2)S. The probe employs a near-infrared cyanine as a fluorophore, and is equipped with an operating azide unit. It is readily employed for assessing intracellular H(2)S levels, and confocal ratiometric imaging is achieved successfully.


Fabiao Yu, Peng Li, Ping Song, Bingshuai Wang, Jianzhang Zhao, Keli Han. An ICT-based strategy to a colorimetric and ratiometric fluorescence probe for hydrogen sulfide in living cells. Chemical communications (Cambridge, England). 2012 Mar 18;48(23):2852-4

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PMID: 22293939

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