Parvin Kumar, Ashwani Kumar, Khalid Hussain
Department of Chemistry, Kururkshetra University, Kurukshetra, Haryana 136119, India. drpkawasthignkc@rediffmail.com
Ultrasonics sonochemistry 2012 JulThis project was undertaken to demonstrate the potential of iodobenzene diacetate for the oxidative aromatization of Hantzch-1,4-dihydropyridines under ultrasonic irradiation. All reactions were carried out under ultrasonic irradiation and results were compared with traditional method. Sonochemical switching was observed in case of oxidative aromatization of 4-n-alkyl substituted 1,4-DHP. Without sonication, dealkylation occurred in case of n-alkyl substituted 1,4-DHP (ionic mechanism) but under ultrasonic irradiation, n-alkyl group was not expelled (radical mechanism). However, secondary alkyl (isopropyl) and benzyl group were expelled under both conditions. Copyright © 2012 Elsevier B.V. All rights reserved.
Parvin Kumar, Ashwani Kumar, Khalid Hussain. Iodobenzene diacetate (IBD) catalyzed an quick oxidative aromatization of Hantzsch-1,4-dihydropyridines to pyridines under ultrasonic irradiation. Ultrasonics sonochemistry. 2012 Jul;19(4):729-35
PMID: 22296993
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