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Minocycline can cause palpebral conjunctival greyish deposits in which autofluorescence can be readily demonstrated. We believe that this is a first report of the demonstration of in-vivo conjunctival autofluorescence of palpebral conjunctival minocycline deposit. In conclusion, minocycline deposit can be shown clinically without the need of an invasive biopsy procedure in patients with a history of blepharitis on long-term tetracycline group of medication presenting with palpebral conjunctival deposits.


Lik Thai Lim, Sonali Tarafdar, Cian E Collins, Fiona Roberts, Kanna Ramaesh. Minocycline induced conjunctival autofluorescence deposition. Seminars in ophthalmology. 2012 Jan-Mar;27(1-2):25-6

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PMID: 22352822

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