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During Drosophila sensory organ precursor cell development, Numb segregates asymmetrically and functions as a cell fate determinant. Recent work now demonstrates in vivo that Numb inactivates Notch by promoting its endocytosis. Copyright © 2012 Elsevier Ltd. All rights reserved.

Citation

Bernd Giebel, Andreas Wodarz. Notch signaling: numb makes the difference. Current biology : CB. 2012 Feb 21;22(4):R133-5

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PMID: 22361152

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