Flexing and stretching in nonribosomal Peptide synthetases.
Sabrina Pfennig, Milton T Stubbs
Institut für Biochemie und Biotechnologie, Martin-Luther-Universität Halle-Wittenberg, Kurt-Mothes-Straße 3, D-06120 Halle (Saale), Germany.
Chemistry & biology 2012 Feb 24Re-engineering of nonribosomal peptide synthetase molecular assembly lines has been hampered by a lack of detailed knowledge concerning inter-domain substrate transfer. Recent structural studies of catalytically relevant domain-domain interactions provide valuable insights into this problem (Liu et al., 2011; Sundlov et al., 2012 [in this issue of Chemistry & Biology]). Copyright © 2012 Elsevier Ltd. All rights reserved.
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Sabrina Pfennig, Milton T Stubbs. Flexing and stretching in nonribosomal Peptide synthetases. Chemistry & biology. 2012 Feb 24;19(2):167-9
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PMID: 22365598
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