Synthesis of functional acetylene derivatives from calcium carbide.

Zhewang Lin, Dingyi Yu, Yin Ngai Sum, Yugen Zhang

Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, Singapore, Singapore.

ChemSusChem 2012 Apr

filter terms:

AHA Erlebnis: CaC(2), used to produce acetylene until several decades ago, is re-emerging as a cheap, sustainable resource synthesized from coal and lignocellulosic biomass. We report efficient catalytic protocols for the synthesis of functional acetylene derivatives from CaC(2) through aldehyde, alkyne, and amine (AAA) as well as alkyne, haloalkane, and amine (AHA) couplings, and in addition demonstrate its use in click and Sonogashira chemistry, showing that calcium carbide is a sustainable and cost-efficient carbon source. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Citation

Zhewang Lin, Dingyi Yu, Yin Ngai Sum, Yugen Zhang. Synthesis of functional acetylene derivatives from calcium carbide. ChemSusChem. 2012 Apr;5(4):625-8