Idiopathic membranoproliferative glomerulonephritis (MPGN) is a rare cause of renal failure with a cumulative incidence of 0.3% of all ESRD and 4% of all primary glomerulonephritis for types I and II. Membranoproliferative glomerulonephritis type III is more uncommon and idiopathic de novo MPGN III in a renal transplant patient has not been reported. We present the case of a 57-year old white female patient with a diagnosis of lithium toxicity as cause of end stage renal disease (ESRD) who developed MPGN III in her allograft 6 years after a renal transplant. Despite treatment, she progressed to ESRD within four and a half years from the time of diagnosis. © 2012 The Authors. Transplant International © 2012 European Society for Organ Transplantation.
Anuja Java, Joseph P Gaut, Daniel C Brennan. De novo membranoproliferative glomerulonephritis III in a renal transplant patient: case report and review of the literature. Transplant international : official journal of the European Society for Organ Transplantation. 2012 May;25(5):e58-61
PMID: 22380572
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