Tissue factor and cardiomyocytes.

Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Zentrum für Herz und Kreislaufmedizin, 12200 Berlin, Germany. ursula.rauch@charite.de

Thrombosis research 2012 May

filter terms:

Tissue factor, the initiator of blood coagulation, plays a major role in the protection of several organs against bleeding. Cardiomyocytes and fibroblasts constitutively express tissue factor. Besides its role for maintain cardiac hemostasis TF has been suggested to have several other important functions in the cardiac muscle. This review summarizes the different roles of TF in the heart with a special focus on pathological conditions. Copyright © 2012 Elsevier Ltd. All rights reserved.