Abnormal skull findings in neural tube defects.

The human neural tube develops and closes during the third and fourth week after conception and is normally completed by 28 days post-conception. Malformations, knows as neural tube defects, occure, when the normal closure process fails. Several clinical types of neural tube defects are recognized, anencefaly and spina bifida being the most common. Such malformations are generally associated with cranial abnormlities.

Citation

Laura Imbruglia, Alessandra Cacciatore, Sabina Carrara, Stefania Recupero, Tindara La Galia, Elisa Maria Pappalardo, Manuela Chiara Accardi, Rosa Pedata, Giusi Rapisarda, Alessia Mammaro. Abnormal skull findings in neural tube defects. Journal of prenatal medicine. 2009 Jul;3(3):44-7

PMID: 22439044

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