Fragrance material review on methyl jasmonate.

J Scognamiglio, L Jones, C S Letizia, A M Api

Research Institute for Fragrance Materials, Inc. 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA. jscognamiglio@rifm.org

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012 Oct

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A toxicologic and dermatologic review of methyl jasmonate when used as a fragrance ingredient is presented. Methyl jasmonate is a member of the fragrance structural group Ketones Cyclopentanones and Cyclopentenones. The common characteristic structural element of the group members is a cyclopentanone or cyclopentenone ring with a straight or branched chain alkane or alkene substituent. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for methyl jasmonate were evaluated then summarized and includes physical properties, acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, phototoxicity, and photoallergy data. A safety assessment of the entire Ketones Cyclopentanones and Cyclopentenones will be published simultaneously with this document; please refer to Belsito et al. (2012) for an overall assessment of the safe use of this material and all Ketones Cyclopentanones and Cyclopentenones in fragrances. Copyright © 2012 Elsevier Ltd. All rights reserved.

Citation

J Scognamiglio, L Jones, C S Letizia, A M Api. Fragrance material review on methyl jasmonate. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2012 Oct;50 Suppl 3:S572-6